Gonadotropin Therapy

Gonadotropins (Gonal-F, Pergonal, Repronex, Humagon) are fertility medications containing follicle-stimulating hormone (FSH) and/or luteinizing hormone (LH). Your physician may prescribe these medications to you if you fail to ovulate or fail to achieve pregnancy with clomiphene citrate therapy. These medications are not available in oral form, but must be administered by either subcutaneous (in the skin) or intramuscular (into the muscle) injection.

Gonadotropins help to stimulate follicular (egg) development within the ovaries. These medications are potent. Typically, patients prescribed this medication must undergo careful monitoring by ultrasound and bloodwork to evaluate follicular development. Gonadotropin therapy is often combined with intrauterine insemination to maximize pregnancy rates. Potential side effects of gonadotropin therapy include ovarian enlargement and abdominal bloating.

If you fail to achieve pregnancy after gonadotropin therapy combined with intrauterine insemination, it may be recommended that you meet with your physician to discuss moving on to more advanced fertility treatment such as in vitro fertilization.


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